
Aisha Khalid
Harvard Medical School, USATitle: Contentious suitability of Prior Cannulated Radial artery as a conduit of choice for CABG
Abstract
Background: Risk of
potential damage to the Radial artery (RA) due to cannulation and contrast is
not mitigated by sophisticated technology or advanced procedural skillset. We
reviewed published literature to probe the effects of trans radial
catheterization on Radial artery’s endothelial physiology and suitability as
conduit for Coronary artery Bypass Grafting (CABG).
Study design and Method: We searched
PubMed and MEDLINE from 1900 till May 2022 to appraise the radial artery
occlusion in trans cannulated artery. Applicable studies were selected, and
data were extracted. The date was synthesized by quantitative pooling and
meta-analysis along with suitable graphic representation. A total of 21 studies
were included. Statistical heterogenicity among meta-analysis studies was
tested by Cochran’s Q test.
Results and Discussion: The incidence
rate of occlusion of RA with prior cannulation is 0.5 to 30 % (1, 2). The
pathological changes like Perivascular inflammation, reactive hyperplasia, and
damage of tunica media of endothelium secondary to contrast agent, even after 3
months of original procedure makes pre-cannulated radial artery, less
favorable conduit for CABG (3). Non-recovery
of vasomotor function of endothelium several months after trans radial
catheterization may limit the use of RA as conduit in CABG surgery (4). Trans radial
catheterization reduces graft patency early on (5) and there was presence of spasm and clots in prior cannulated RA
proved by Kamiya et al whereas the incidence of moderate to severe Radial
artery spasm usually associated with multiple punctures attempts and usage of
large-bore sheath (6, 7).
Conclusion: Radial artery is
the graft of choice, after Left internal Mamillary Artery (LIMA) in most big
multicenter globally (8). After
above mentioned evidence, cardiologist may need to be obligated to avoid RA
where possible especially when early CABG is indicated.
Biography
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