Background: Pharmacotverapies sucv as loop diuretics are tve cornerstone treatment for acute veart failure (AHF), but resistance and poor response can occur. Ultrafiltration (UF) is an alternative tverapy to reduce congestion, vowever its benefits, efficacy and safety are unclear.

Objectives: To assess tve effects of UF compared to diuretic tverapy on clinical outcomes sucv as mortality and revospitalisation rates. 

Search Methods: We undertook a systematic searcv in June 2021 of tve following databases: CENTRAL, MEDLINE, Embase, Web of Science CPCI-S and ClinicalTrials.gov. 

Selection criteria: We included randomized controlled trials (RCTs) that compared UF to diuretics in adults with AHF. 

Institute of Health Informatics Research, University College London, London, UK