Virtual Conference
Heart 2022 Conference

Pavlo Kydon

Poltava state medical university, Ukraine

Title: Features of cardiac conduction during psychomotor agitation in patients with paranoid schizophrenia


Introduction: Arrhythmias and conduction disturbance are one of the most complex and urgent problems of modern cardiology. It is generally recognized that the main etiological factors of arrhythmias are heart disease. However, in some cases, even the use of modern research methods does not detect pathological changes in the heart, which indicates the existence of extracardial factors, among which neurogenic factors occupy a significant place. However, the pathophysiological mechanism of neuronal involvement in the pathogenesis of cardiovascular disease remains unclear. It can be assumed that along with the existence of cerebrocardial connections, it is possible to have positive potentiating cardiocerebral influences from the "target organ".

The aim of the work was to study the effect of psychopathological symptoms, in particular psychomotor agitation, on cardiac conduction in persons without concomitant pathology of the cardiovascular system.

Materials and methods: 
32 patients with a diagnosis of schizophrenia, paranoid form (F20.0), who received inpatient psychiatric care, were examined. Concomitant cardiac pathology in patients was absent. The main methods of research were electrocardiographic and clinical-psychopathological.

Results and discussion: It was found that psychopathological symptoms, especially in the presence of psychomotor agitation, adversely affects the heart activity in somatic healthy individuals. It causes an extension of The QTc interval (p?0,05) and nonspecific changes in the ST segment and the T wave (p?0,05), which indicate violations of conduction and repolarization.

Identified in the course of this study data should be taken into account during the choice of therapy for psychomotor agitation of patients with schizophrenia, especially in the presence of concomitant pathology of the cardiovascular system.


I, Kydon Pavlo, was born in 1987. I graduated from HSEEU "Ukrainian medical stomatological academy" with a specialty in "General medicine" in 2010. From 2010 to 2012, I studied at an internship in the specialty "Psychiatry". Since 2012, I worked as a senior laboratory assistant at the Department of Psychiatry, Narcology, and Medical Psychology of the UMSA. From September 1, 2019, I was transferred to the position of associate lecturer of this department. In 2019, I received PhD degree on the topic "Clinical-psychopathological and pathopsychological characteristics of patients with paranoid schizophrenia, combined with cannabinoids use" on specialty "Psychiatry".