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Ahmad Qasem

Macquarie University , Australia

Title: Derivation of Central Aortic Pressure non-invasively

Abstract

Measuring blood pressure in the arm is an essential part of clinical assessment of the cardiovascular system. However, based on hemodynamic principles, blood pressure in the arm differs significantly from the blood pressure the heart faces in the aortic artery. The difference in systolic pressure between brachial (arm) and central aortic arteries can range from 5 mmHg to 30 mmHg, even with similar brachial systolic pressure. Measuring aortic pressure pulse with features will provide an insight into cardiac and vascular health beyond the brachial blood pressure measurements. Central aortic pressure is usually measured invasively using catheterization.  A method has been developed to estimate central aortic pressure waveform from non-invasively recorded peripheral arterial pulses based on harmonic analysis, hemodynamic, and fluid dynamic principles.  This non-invasive tool has been shown to accurately reproduce the invasive central pulses even with maneuvers changing peripheral blood pressure and arterial status. The talk will focus on the methods and their application on other sensors, their validation, clinical reliability, and published studies showing the clinical efficacy of the non-invasive central aortic pressure waveform parameters. The talk will address the future implications of utilizing this method in wearable sensors, such that detecting these cuffless yet pressure-related parameters in wearable technology will have significant health benefits for general users. 
 

Biography

Ahmad Qasem graduated from the University of Massachusetts, North Dartmouth, Massachusetts, in 1987 and 1989 with Bachelor (magna cum Laude) and Master (cum laude) degrees in electrical engineering, respectively. In 1997, he was awarded an Industrial Australian Post-Graduate scholarship to study for a Ph.D. in biomedical engineering at the Graduate School of Biomedical Engineering at the University of New South Wales (UNSW), Sydney, Australia. He received a Ph.D. in “Non-invasive Assessment of the Cardiovascular System.” in 2001.   From 2002, he worked at AtCor Medical, an Australian company focused on non-invasive medical devices to assess cardiovascular systems, as the company's chief science and research officer.  His work resulted in 9 US patents and applications implemented in the AtCor FDA-cleared medical devices SphygmoCor and XCEL.  He have over 22 years of experience in research cardiovascular dynamics & mathematical modeling. I have written and co-wrote over 90 publications and presentations in American and European scientific, engineering & medical peer-reviewed journals. I am an honorary senior Research Fellow with the Faculty of Medicine and Health Sciences at Macquarie University, Sydney.