Dr. Mahrukh Mansoor Khosa
Basildon University Hospital , United KingdomPresentation Title:
Clinical Outcomes Of Early Versus Delayed Discharge after Primary Percutaneous Coronary Intervention
Abstract
Background: ST-Elevation Myocardial Infarction (STEMI) remains a leading cause of death, particularly in developing countries. Primary Percutaneous Coronary Intervention (PCI) is a well-established treatment for STEMI. Traditionally requiring overnight monitoring, recent advancements have enabled earlier discharge without compromising patient safety. This study aimed to compare clinical outcomes of early versus delayed discharge after primary PCI in STEMI patients, and to determine the frequency and safety of early discharge.
Methodology: This prospective observational study was conducted at the Punjab Institute of Cardiology, Lahore, from August 2020 to February 2021. A total of 200 patients aged 35–65 years presenting with STEMI and undergoing primary PCI were enrolled. Early discharge was defined as within 36 hours post-PCI. Clinical outcomes—recurrent myocardial infarction, stroke, heart failure, and mortality—were assessed after 1-month follow-up. Statistical analysis was performed using SPSS v25.0, with chi-square testing and stratification by demographics and comorbidities.
Results: Out of 200 patients, 86 (43%) were discharged early and 114 (57%) had delayed discharge. No significant differences in adverse outcomes were observed between the two groups. Recurrent MI occurred in 9.3% of early discharges versus 1.8% of delayed (p=0.015), but rates of stroke, heart failure, and mortality did not differ significantly (p>0.05). The study demonstrated that early discharge is generally safe and feasible in selected STEMI patients post-PCI.
Conclusion: Early discharge following primary PCI is a safe and cost-effective strategy in appropriately selected STEMI patients. Implementation of early discharge protocols may improve resource utilization and reduce healthcare burden without compromising patient outcomes.
Biography
Dr. Mahrukh is currently working as a Specialty Doctor in Cardiology at Basildon University Hospital, Essex, United Kingdom. She completed her MBBS and FCPS in Cardiology from Pakistan and also holds the Membership of the Royal Colleges of Physicians (MRCP) diploma from the United Kingdom. With a strong academic and clinical background in cardiovascular medicine, she has developed particular interest in interventional cardiology and patient outcome optimization. Her work focuses on improving healthcare delivery through evidence-based practices and efficient patient management strategies. She has been actively involved in clinical audits and research studies related to STEMI management and percutaneous coronary interventions.
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