Dr. Suvendu Chattopadhyay
Manipal Hospital, IndiaPresentation Title:
Incidence of coronary artery disease among copd patients with uncontrolled dyspnoea despite optimal bronchodilator therapy
Abstract
Introduction: Both coronary artery disease (CAD) and chronic obstructive pulmonary disease (COPD) have high rates of morbidity and mortality. Systemic inflammation, as demonstrated in several studies of COPD patients, is also associated with atherosclerotic plaque formation. Various studies had demonstrated varying incidence of CAD among COPD patients. However, it is unclear that how much contribution of CAD is responsible for the worsening of COPD symptoms.
Aim & objective: To assess the incidence of coronary artery disease in individuals with COPD who have uncontrolled dyspnoea even with the optimal bronchodilator treatment.
Materials & Methods: This study was a hospital based observational study, cross sectional in design. This study was carried out on established COPD patients with uncontrolled dyspnoea despite optimal bronchodilator therapy for > 3 months with good adherence. History of typical angina, moderate to severe pulmonary hypertension, established CAD without revascularization or left ventricular systolic dysfunction (EF<50%) cases were excluded. Finally, 120 consecutive patients fulfilling the selection criteria were includes and underwent coronary angiography.
Result: The study population was male predominant (67.5%), coronary angiography showed 78 out of 120 (65%) COPD patients who had uncontrolled dyspnoea despite optimal medical management for COPD, had critical coronary artery disease. Among various common risk factors smoking and diabetes were significantly associated with critical CAD (p value 0.00023 and 0.0045 respectively). Ischaemic pattern in ECG was present only in 48.3% cases.
Conclusion: Significant co-association of critical CAD was found in COPD patients who remained symptomatic despite adequate bronchodilator medication; therefore, coronary angiography should be done in those cases.
Biography
Dr. Suvendu Chattopadhyay has completed his MBBS from prestigious IPGMER, Kolkata in 2012, DNB in Pulmonary medicine in 2017 and DM in cardiology in 2020. After completing 3 years senior resident-ship in cardiology at IPGMER (2020-23), presently he is practicing as consultant interventional cardiologist in Manipal Hospital Broadway Kolkata, Charnock Hospital, Kolkata and B M Birla Heart research centre, Kolkata. He has performed more than 5000 coronary and peripheral angiography, more than 1000 angioplasty, more than 500 permanent pacemaker implantation and more than 50 AICD/CRT implantation. He has also performed more than 100 bronchoscopy and more than 50 medical thoracoscopy during his residency in pulmonary medicine. He has may publications in various peer reviewed journals. He gives his deliberate lecture in various CMEs regularly. He has attended many national and state level conferences as speaker or panellist. He is dedicated to his patients with a strong determination for academic and professional upgradation.
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