Dragan NovoselFaculty of Medicine in Osijek, Croatia
Title: The aim of the study was to develop a diagnostic approach to assessing the nature of ischemic mitral regurgitation (reversible/irreversible), allowing to predict its dynamics after myocardial revascularization. Material and methods. The study included 105 patients with coronary artery disease and ischemic mitral regurgitation (MR) who underwent examination and surgical treatment. Two groups of pat
We conducted a cohort study on 260 subjects with heart failure who were hospitalized at the Department of Cardiovascular Diseases of the Clinical Hospital Center Osijek for a period of 7 years. At hospitalization, subjects were initially assigned functional status using the SPPB (Short Physical Performance Battery) by clinicians, and mortality was determined at the end of the five-year follow-up period. The median SPPB value in surviving subjects was 4 with an interquartile range of 2 to 6, while the median SPPB value of deceased subjects was 2 with an interquartile range of 2 to 4, with a P-value of 0.001 indicating a clear link between functional status and mortality over a five-year period. The serum level of galectin-3 was determined in 177 subjects. The SPPB did not show a statistically significant correlation with the serum level of galectin-3 (P = 0.645). There was no statistically significant difference in the serum value of galectin-3 between the groups of deceased and survivors (P = 0.472). We can conclude that SPPB is an excellent, affordable, and inexpensive measuring instrument for predicting 5-year mortality in patients with heart failure, and it is superior to galectin-3 serum levels.