
Dragan Novosel
Faculty of Medicine in Osijek, CroatiaTitle: The aim of the study was to develop a diagnostic approach to assessing the nature of ischemic mitral regurgitation (reversible/irreversible), allowing to predict its dynamics after myocardial revascularization. Material and methods. The study included 105 patients with coronary artery disease and ischemic mitral regurgitation (MR) who underwent examination and surgical treatment. Two groups of pat
Abstract
We conducted a cohort study on 260 subjects
with heart failure who were hospitalized at the Department of Cardiovascular
Diseases of the Clinical Hospital Center Osijek for a period of 7 years. At
hospitalization, subjects were initially assigned functional status using the
SPPB (Short Physical Performance Battery) by clinicians, and mortality was
determined at the end of the five-year follow-up period. The median SPPB value
in surviving subjects was 4 with an interquartile range of 2 to 6, while the
median SPPB value of deceased subjects was 2 with an interquartile range of 2
to 4, with a P-value of 0.001 indicating a clear link between functional status
and mortality over a five-year period. The serum level of galectin-3 was
determined in 177 subjects. The SPPB did not show a statistically significant
correlation with the serum level of galectin-3 (P = 0.645). There was no
statistically significant difference in the serum value of galectin-3 between
the groups of deceased and survivors (P = 0.472). We can conclude that SPPB is
an excellent, affordable, and inexpensive measuring instrument for predicting
5-year mortality in patients with heart failure, and it is superior to
galectin-3 serum levels.
Biography
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