Ganbaatar Battsetseg
Mongolian National University of Medical Sciences, MongoliaPresentation Title:
Association between arterial hypertension and cognitive impairment: A preliminary study
Abstract
Background: Arterial hypertension (AH) is a major risk factor for cardiovascular morbidity and mortality, with a rapidly increasing prevalence in low- and middle-income countries. Beyond its well-established cardiovascular consequences, AH has been implicated in cerebrovascular dysfunction and cognitive impairment. This study aims to conduct a preliminary evaluation of the association between arterial hypertension and cognitive function.
Methods: This cross-sectional observational study included 30 patients aged 30–60 years who attended Shinonmed Hospital. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE). Blood pressure parameters, including systolic blood pressure (SBP) and diastolic blood pressure (DBP), were recorded. Lipid profile markers, such as total cholesterol and triglycerides, were analyzed. Carotid intima-media thickness (IMT) was measured using a GE LOGIQ P9 ultrasound system. Statistical analyses included ANOVA, paired t-tests, and Pearson correlation coefficients.
Results: Of the 30 participants, 15 were diagnosed with hypertension, while 15 had normotensive blood pressure levels. Key findings from the study include:
• Higher SBP was significantly associated with lower MoCA scores (r = -0.39, p = 0.033).
• Elevated cholesterol levels exhibited a strong negative correlation with MoCA scores (r = -0.68, p < 0.001).
• No significant correlation was observed between triglyceride levels and MoCA scores (p = 0.86).
• No statistically significant difference in MoCA scores was found between individuals receiving antihypertensive treatment and those not on medication (p = 0.60).
• IMT did not show a statistically significant correlation with cognitive function (r = -0.24, p = 0.19).
Conclusion: The findings suggest a potential adverse effect of arterial hypertension on cognitive function. Moreover, elevated serum cholesterol levels appear to be strongly associated with cognitive impairment, underscoring the necessity for further research. Given the weak correlation between IMT and cognitive performance, larger-scale investigations are warranted to clarify this relationship.
Biography
G.Battsetseg has completed her Master of science in medicine at the age of 41 years from Mongolian National University of Medical Sciences. She is the cardiologist of Shinonmed hospital. She has published more than 2 papers in reputed journals and has been serving as an editorial board member of repute. After earning a MD, G.Battsetseg pursued postgraduate specialization in cardiology. In addition to clinical practice, Dr.Battsetseg actively contributes to medical education and has participated in several national cardiology conferences. I`m passionate about preventive cardiology and lifestyle interventions, Dr . Battsetseg emphasizes holistic patient care and long-term heart health.
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