Guilherme Séer da Silva
Dante Pazzanese Institute of Cardiology , BrazilTitle: Mitral valve prolapse arrhythmogenic syndrome
Abstract
There is an association between mitral valve prolapse (MVP) and sudden cardiac death. It is prudent to identify and stratify patient at risk. Among the risk factors were female gender, electrocardiographic abnormalities, presence of myocardial fibrosis seen by magnetic resonance imaging and mitral annulus disjunction diagnosed by echocardiogram and/or magnetic resonance imaging. Most patients who develop sudden death associated with MVP have evidence of a “trigger” (premature ventricular contractions) associated with a substrate (myocardial deformation or fibrosis secondary to mitral annulus disjunction) necessary to initiate and perpetuate malignant ventricular arrhythmias. Future longitudinal studies are needed to advance our understanding of the mechanisms involved in sudden death associated with MVP, to validate existing risk factors, and to identify high-risk patients who could potentially benefit from intervention for primary prevention of sudden death.
Biography
Guilherme Séer da Silva has completed his specialty in Cardiology at the age of 30 years at Dante Pazzanese Institute of Cardiology in São Paulo, Brazil, in 2020 and completed the Fellowship in Valvular Heart Disease also at the same institution in 2021. Currently 34 years old, he works as an assistant professor in the valvular heart disease department at the Dante Pazzanese Institute of Cardiology and has already had important publications, including for the medical journal of the Cardiology Society of the State of São Paulo (SOCESP Journal), whose congress is one of the most renowned in Brazil, and also posters for the American College of Cardiology Congress (ACC 2021). In addition to being the author of a chapter on Mitral Valve Prolapse in a national cardiology book. He also works in the intensive care unit of a hospital in São Paulo.
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