Juan Armando D Diaz
Makati Medical Center, PhilippinesPresentation Title:
LV-GLS as predictor for outcomes in Covid-19
Abstract
Background: Establishing a correlation between left ventricular global longitudinal strain(LV-GLS) with transthoracic echocardiography(TTE), and the severity and outcomes of patients infected with COVID-19 offers several advantages in patient care and management. This study aims to explore the utility of measuring the LV-GLS to predict outcomes in hospitalized patients infected with COVID-19.
Methods: This was a retrospective cohort study of COVID-19 patients in a tertiary care center who had a TTE with GLS measurements from April 2021 to May 2021. Comparisons between parameters of left ventricular function (GLS and LVEF) were performed using the t-test or Mann-Whitney U test for continuous variables and the c2 test or Fisher exact test for categorical variables. Kaplan-Meier survival analysis was used to estimate mortality and length of hospital stay. Log-Rank test was used to assess the association of GLS on in-hospital mortality.
Results: A total of 124 participants were included in the study. 73.2% (90/123) had a decreased GLS; average GLS was -19.2% [-27.6 to -4.7]. A significant model was created using GLS as a main factor with pre-selected covariates with a Wald c2 (2, N = 121) = 7.932 (p = .020). Co-variates were average GLS magnitude (HR = 0.897 [95% CI 0.808 to 0.997], p = .0.043) and presence of severe complications (HR = 2.630 [95% CI of 1.087 to 6.362], p = 0.032).
Conclusions: A model considering severe complications showed that among patients admitted for COVID-19 an abnormal average global longitudinal strain predicts increased in-hospital mortality.
Biography
Juan Armando Diaz Completed his Medical Degree at the University of the Philippines College of Medicine in 2011 and went on to finish his training in Internal Medicine and Cardiology at the Makati Medical Center, Philippines. He completed his clinical research fellowship in Echocardiography in the same institution before pursuing clinical training in Interventional Cardiology and Transcatheter aortic Valve replacement at the Sapporo Cardiovascular Clinic, Sapporo, Japan. He is currently the head of the Cardiovascular Diagnostics (Heart Station) of the Our Lady of Mount Carmel Medical Center, Pampanga, Philippines.
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