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Noushin Mohammadifard

Isfahan University of Medical Sciences, Iran

Presentation Title:

Eating Habits and Premature Coronary Artery Disease Risk

Abstract

There is limited evidence regarding prevalent dietary behaviors and their relationship with premature coronary artery disease (PCAD) in the Iranian population. This study aimed to examine the association between a composite eating habits score (EHS) and the risk of developing PCAD. In this multicenter case-control investigation, 3,200 individuals were enrolled, comprising patients diagnosed with PCAD and healthy controls, all confirmed through coronary angiography. PCAD was defined as the presence of ≥75% stenosis in at least one coronary artery or ≥50% in the left main artery. Dietary habits were evaluated through structured interviews, and higher EHS values reflected healthier eating behaviors. Statistical analyses adjusting for potential confounding variables revealed that participants in the highest EHS quartile had a 22% reduced risk of PCAD compared to those in the lowest quartile (95% CI: 0.61–0.99; P = 0.024). Among the individual behaviors examined, avoiding salt at the table (OR = 0.80, 95% CI: 0.66–0.97; P = 0.023), consuming low-salt meals (OR = 0.75, 95% CI: 0.57–0.99; P = 0.022), and eating slowly (OR = 0.42, 95% CI: 0.24–0.71; P < 0.001) were linked with significantly lower odds of PCAD. Conversely, drinking more water (OR = 1.56, 95% CI: 1.07–2.27; P = 0.013) and eating more frequently (OR = 1.85, 95% CI: 1.09–3.13; P = 0.025) were associated with elevated PCAD risk. These findings suggest that an overall healthier eating pattern, especially lower salt consumption and slower eating pace, may contribute to a reduced likelihood of premature coronary artery disease. Prospective studies are needed to confirm these associations and further explore dietary behaviors influencing early-onset coronary disease.
 
 

Biography

Dr. Noushin Mohammadifard is an Associate Professor and Head of the Nutrition Department at the Cardiovascular Research Institute (CRI), Isfahan University of Medical Sciences (IUMS), Iran, a WHO Collaborating Center for Cardiovascular Disease Prevention. She also serves as the Deputy Director of CRI. With a Ph.D. in Nutrition Science from IUMS, her research focuses on dietary determinants of cardiometabolic health and community-based interventions on CVD outcomes.

Dr. Mohammadifard has led several large studies, including the Isfahan Healthy Heart Program (IHHP), a WHO-endorsed model for developing countries, and the Isfahan Cohort Study (ICS), as well as contributing to multicentric international study of Prospective Urban Rural Epidemiological (PURE) study. She has published over 270 peer-reviewed articles, some books, serves on the editorial boards of several international journals, and has been a keynote speaker at international conferences. Her work is internationally recognized, placing her among the most highly cited researchers in her field.