
Noushin Mohammadifard
Isfahan University of Medical Sciences, IranPresentation Title:
Eating Habits and Premature Coronary Artery Disease Risk
Abstract
There is limited evidence regarding
prevalent dietary behaviors and their relationship with premature coronary
artery disease (PCAD) in the Iranian population. This study aimed to examine
the association between a composite eating habits score (EHS) and the risk of
developing PCAD. In this multicenter case-control investigation, 3,200
individuals were enrolled, comprising patients diagnosed with PCAD and healthy
controls, all confirmed through coronary angiography. PCAD was defined as the
presence of ≥75% stenosis in at least one coronary artery or ≥50% in the left
main artery. Dietary habits were evaluated through structured interviews, and
higher EHS values reflected healthier eating behaviors. Statistical analyses
adjusting for potential confounding variables revealed that participants in the
highest EHS quartile had a 22% reduced risk of PCAD compared to those in the
lowest quartile (95% CI: 0.61–0.99; P = 0.024). Among the individual behaviors
examined, avoiding salt at the table (OR = 0.80, 95% CI: 0.66–0.97; P = 0.023),
consuming low-salt meals (OR = 0.75, 95% CI: 0.57–0.99; P = 0.022), and eating
slowly (OR = 0.42, 95% CI: 0.24–0.71; P < 0.001) were linked with
significantly lower odds of PCAD. Conversely, drinking more water (OR = 1.56,
95% CI: 1.07–2.27; P = 0.013) and eating more frequently (OR = 1.85, 95% CI:
1.09–3.13; P = 0.025) were associated with elevated PCAD risk. These findings
suggest that an overall healthier eating pattern, especially lower salt
consumption and slower eating pace, may contribute to a reduced likelihood of
premature coronary artery disease. Prospective studies are needed to confirm
these associations and further explore dietary behaviors influencing
early-onset coronary disease.
Biography
Dr. Noushin Mohammadifard is an Associate Professor and Head of the Nutrition Department at the Cardiovascular Research Institute (CRI), Isfahan University of Medical Sciences (IUMS), Iran, a WHO Collaborating Center for Cardiovascular Disease Prevention. She also serves as the Deputy Director of CRI. With a Ph.D. in Nutrition Science from IUMS, her research focuses on dietary determinants of cardiometabolic health and community-based interventions on CVD outcomes.
Dr. Mohammadifard has led several large studies, including the Isfahan Healthy Heart Program (IHHP), a WHO-endorsed model for developing countries, and the Isfahan Cohort Study (ICS), as well as contributing to multicentric international study of Prospective Urban Rural Epidemiological (PURE) study. She has published over 270 peer-reviewed articles, some books, serves on the editorial boards of several international journals, and has been a keynote speaker at international conferences. Her work is internationally recognized, placing her among the most highly cited researchers in her field.