Virtual Conference
Heart 2022 Conference

Vira Shuper

Bucovinian State Medical University, Ukraine

Title: Investigation of the adherence to prescribed treatment of the patients with Coronary Heart disease


Introduction: Most reasons of deaths all over the world can be attributed to chronic diseases. Approximately half of patients with chronic diseases do not take their medication as prescribed. Many researches have shown that non-adherence leads to increased morbidity, mortality and the cost of healthcare. Coronary heart disease (CHD) has become a global health problem and a primary cause of morbidity and premature death worldwide. The levels of non-adherence among patients with CHD is typically in the range of 33%–50%. Non-adherence to secondary prevention medications has been associated with a 10%–40% increase in the risk of cardiac hospitalization and a 50%–80% increase in mortality [1-9].

The aim of the work was to investigate the adherence to secondary prevention medications among patients with Coronary Heart disease and identify factors associated with it.

Materials and methods: We examined 40 patients diagnosed with CHD with age more than 50 years old, which has been prescribed with optimal medication for 1 year during hospitalization. Patients` adherence was defined according to MMS-8 Morisky values for secondary prevention medications prescribed by doctors. Also, questionnaires about individual reasons of non-compliance and for individual patient`s opinion about importance and usefulness of knowledge according risk factors of the increase cardiovascular mortality was designed and proposed to the patients. Simple descriptive statistics were used to elucidate the characteristics of the patient population and results from individual adherence tools [10]. Final score was analyzed and correlation between patients’ data and level of adherence to prescribed treatment were identified. A correlation matrix (using Spearman’s coefficient) was reviewed for any evidence of collinearity.

Conclusions and prospects for further research in this direction: Despite a rather small and short-term study, received results can provide useful practical information on the prevalence and severity of adherence disorders among patients with coronary heart disease. Analysis of the factors influencing the adherence of cardiovascular patients has demonstrated the main reasons from patients and healthcare professionals affecting the level of compliance with the prescribed treatment. The step towards improving adherence can be initiated by the healthcare professional to overcome the patient's concerns about the prescribed medication (taking into account the amount and level of information tailored to individual needs) and to improve understanding of the disease and medication, which will help solve the problem of clear continuation of prescribed treatment. Non-compliance with treatment may not be directed to the whole complex but to partial drugs. This necessitates personal monitoring of patients by healthcare professionals in the form of regular inspections of intentional and unintentional non-adherence, including factors and reasons that may change and lead to such behavior. Concerns and difficulties with medication should be addressed even in patients who have the adherent behavior to prescribed treatment.


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