Virtual Conference
Heart 2022 Conference

Wongwaris Aphijirawat

Queen Sirikit Naval Hospital, Thailand

Title: Effect of Resistance Exercise With Rubber band in Chronic Heart Failure With Preserved Ejection Fraction Patients


BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a disease which common in elderly population with multiple comorbidities. Exercise intolerance and easily fatigue were important problems in this population leading to poor quality of life (QoL). Despite increasing incidence, many drug trials fail to show efficacy in these patients. Resistant exercise, by weight-training, can improve QoL but it is not suitable for all patients. Rubber band is safe and easy access home-based exercise which can improve frailty in HFrEF. We sought to evaluate the effect of rubber band exercise to improve exercise capacity in HFpEF population.

METHODS: We conducted a prospective, randomized, open-labeled, blinded endpoints (PROBE) design to determine whether 3-month of resistance exercise using rubber band can improve exercise capacity in stable HFpEF patients compared with standard usual care. The co-primary outcome measured by peak oxygen consumption (peak VO2 max) and 6-minute walk distance (6mwd) were evaluated. The secondary endpoint is the change in NT-proBNP level, total exercise time and safety of exercise.

RESULTS: A total of 32 patients underwent randomization in 1:1 ratio. Baseline characteristics in both groups were not difference. The overall adherence to exercise was excellent (93%). Exercise capacity were improved in both groups. There was significant different in peak O2 consumption (29.97±3.98 vs 26.1 ± 4.2 ml/kg·min, p=0.048).  Six-minute walk distance was not difference (380 ± 63 vs 427 ± 73 m, p = 0.327). The secondary endpoint, serum NT-proBNP level (141 vs 253, p =0.7) and exercise time (292 vs 321.5 s, p=0.464) were not difference in rubber band exercise group when compared with standard usual care.

CONCLUSION: In stable chronic HFpEF patients, resistance exercise using rubber band shows significant improved in peak VO2 max after 3-month exercise program when compared with standard usual care.


Wongwaris Aphijirawat has completed his MD at the age of 35 years from Phramongkutklao College of Medicine, Thailand. He is the interventional cardiologiost consultant of Queen Sirikit Naval Hospital, Thailand.